Abstract
Three new sesquiterpenoids, isodauc-7(14)-en-6alpha,10beta-diol (1), 10beta-hydroxyisodauc-6-en-14-al (2), and (7S(*))-opposit-4(15)-en-1beta,7-diol (4), along with ten known compounds have been isolated from the aerial parts of Senecio argunensis. Their structures were established by means of detailed spectroscopic analysis including IR, HR-MS, and 1D NMR and 2D NMR data. The sesquiterpenoids were assayed against Escherichia coli, Staphylococcus aureus and Bacillus subtilis. Compounds 4 exhibited weak antibacterial activity against Escherichia coli and Bacillus subtilis.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Bacterial Agents / chemistry*
-
Anti-Bacterial Agents / isolation & purification
-
Anti-Bacterial Agents / pharmacology
-
Magnetic Resonance Spectroscopy
-
Microbial Sensitivity Tests
-
Molecular Conformation
-
Plant Extracts / chemistry
-
Senecio / chemistry*
-
Sesquiterpenes / chemistry*
-
Sesquiterpenes / isolation & purification
-
Sesquiterpenes / pharmacology
Substances
-
(7S*)-opposit-4(15)-en-1beta ,7-diol
-
10beta-hydroxyisodauc-6-en-14-al
-
Anti-Bacterial Agents
-
Plant Extracts
-
Sesquiterpenes
-
isodauc-7(14)-en-6alpha,10beta-diol