Monocular and binocular contrast sensitivities were measured in patients with uniocular cataract. The cataractous eye showed a greater monocular loss at higher spatial frequencies compared to lower spatial frequencies. Binocular contrast sensitivity depended on the contrast sensitivity differences between the two eyes. At low spatial frequencies, where the monocular sensitivity difference was minimal, binocular summation was obtained. As the sensitivity difference increased at higher spatial frequencies, the binocular contrast sensitivity decreased steadily until it reached a level below the sensitivity of the cataractous eye, demonstrating binocular inhibition. The clinical implications of binocular inhibition obtained with uniocular cataract are discussed.