Weekly low-dose methotrexate therapy for cutaneous sarcoidosis

J Am Acad Dermatol. 1991 Mar;24(3):451-4. doi: 10.1016/0190-9622(91)70071-9.

Abstract

Three patients with severe, treatment-resistant cutaneous sarcoidosis were treated with low-dose oral methotrexate on a weekly basis. Facial granulomas and ulcerations responded best. A response was apparent after several weeks of treatment, but 6 to 9 months were required to reach maximal effect.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adult
  • Drug Administration Schedule
  • Female
  • Granuloma / drug therapy
  • Humans
  • Male
  • Methotrexate / administration & dosage*
  • Methotrexate / therapeutic use
  • Middle Aged
  • Sarcoidosis / drug therapy*
  • Sarcoidosis / pathology
  • Skin Diseases / drug therapy*
  • Skin Diseases / pathology
  • Ulcer / drug therapy

Substances

  • Methotrexate