Medical applications of epidermal stem cells

In: StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008–.


The skin epidermis, like many other epithelia, continues to self-renew throughout the life of the animals due to the presence of adult stem cells that provide new cells to replace the damaged or dead cells. Following wounding, the skin is able to regenerate itself to some degree. However, when the wound is too extensive, such as in third-degree burns or in some skin genetic diseases, the skin cannot repair itself properly without medical interventions. The purpose of this chapter is to highlight the recent medical progresses that have been developed to regenerate the skin using stem cell technologies.

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