Thyrotoxic periodic paralysis (TPP) in a 28-year-old sudanese man started on prednisone

J Am Board Fam Med. 2010 Jul-Aug;23(4):551-4. doi: 10.3122/jabfm.2010.04.090220.

Abstract

Thyrotoxic periodic paralysis is a rare complication associated with hyperthyroidism. It is most common in the Asian population. We describe a case of a 28-year-old Sudanese man who presented with ascending lower extremity paralysis after treatment of hyperthyroidism with prednisone and methimazole. This case report reviews the literature looking at pathophysiology, causes, and treatment recommendations for this rare complication of hyperthyroidism.

Publication types

  • Case Reports

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Adult
  • Anti-Inflammatory Agents / adverse effects
  • Anti-Inflammatory Agents / therapeutic use
  • Humans
  • Hyperthyroidism / blood*
  • Hyperthyroidism / drug therapy
  • Hypokalemia / blood
  • Hypokalemia / drug therapy
  • Hypokalemic Periodic Paralysis / blood
  • Hypokalemic Periodic Paralysis / drug therapy
  • Hypokalemic Periodic Paralysis / etiology*
  • Male
  • Paralysis / etiology
  • Potassium Chloride / therapeutic use*
  • Prednisolone / adverse effects*
  • Prednisolone / therapeutic use
  • Propranolol / therapeutic use*

Substances

  • Adrenergic beta-Antagonists
  • Anti-Inflammatory Agents
  • Potassium Chloride
  • Prednisolone
  • Propranolol