Only the strong survive

Immunity. 2010 Jun 25;32(6):729-31. doi: 10.1016/j.immuni.2010.06.010.


Whether apoptosis is relevant for interclonal competition of T cells after antigen encounter has remained uncertain. In this issue of Immunity, Wensveen et al. (2010) establish a critical role for the proapoptotic BH3-only protein Noxa in this selection process.

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