Incidence of multiple sclerosis in Hordaland, western Norway: a fluctuating pattern

Neuroepidemiology. 1991;10(2):53-61. doi: 10.1159/000110247.


The incidence of multiple sclerosis (MS) was studied in the county of Hordaland, western Norway. A significant increase in incidence in the period 1958-1987, a decline followed by a gradual increase in mean age at onset, geographic differences in time trends and a biphasic pattern revealed by a birth cohort analysis support the theory of real time-space fluctuations in the incidence of MS over time.

MeSH terms

  • Adult
  • Cross-Cultural Comparison*
  • Cross-Sectional Studies
  • Humans
  • Incidence
  • Multiple Sclerosis / classification
  • Multiple Sclerosis / epidemiology*
  • Multiple Sclerosis / etiology
  • Norway / epidemiology
  • Risk Factors
  • Rural Population
  • Urban Population