Genome variation and complexity in the autism spectrum

L N van de Lagemaat; Seth G N Grant

doi:10.1016/j.neuron.2010.06.026

Genome variation and complexity in the autism spectrum

Neuron. 2010 Jul 15;67(1):8-10. doi: 10.1016/j.neuron.2010.06.026.

Authors

L N van de Lagemaat¹, Seth G N Grant

Affiliation

¹ Genes to Cognition Programme, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridgeshire, UK.

PMID: 20624587
DOI: 10.1016/j.neuron.2010.06.026

Abstract

A large international consortium reports in Nature on the diversity of genomic changes in families with autism spectrum disorders. Inherited and de novo mutations affecting many genes were discovered implicating disruption to postsynaptic and cellular signaling processes.