Sorafenib Induces Sustained Molecular Remission in FLT3-ITD Positive AML With Relapse After Second Allogeneic Stem Cell Transplantation Without Exacerbation of Acute GVHD: A Case Report

Leuk Res. 2010 Oct;34(10):e270-2. doi: 10.1016/j.leukres.2010.04.011. Epub 2010 Jun 2.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Antineoplastic Agents / therapeutic use*
  • Benzenesulfonates
  • Female
  • Graft vs Host Disease
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy*
  • Leukemia, Myeloid, Acute / genetics
  • Leukemia, Myeloid, Acute / metabolism
  • Niacinamide / analogs & derivatives
  • Phenylurea Compounds
  • Point Mutation*
  • Protein Kinase Inhibitors / therapeutic use*
  • Pyridines
  • Recurrence
  • Sorafenib
  • Transplantation, Homologous
  • fms-Like Tyrosine Kinase 3 / antagonists & inhibitors
  • fms-Like Tyrosine Kinase 3 / genetics*

Substances

  • Antineoplastic Agents
  • Benzenesulfonates
  • Phenylurea Compounds
  • Protein Kinase Inhibitors
  • Pyridines
  • Niacinamide
  • Sorafenib
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3