Computer-assisted navigation in bone tumor surgery: seamless workflow model and evolution of technique

Clin Orthop Relat Res. 2010 Nov;468(11):2985-91. doi: 10.1007/s11999-010-1465-7.

Abstract

Background: Computer-assisted navigation was recently introduced to aid the resection of musculoskeletal tumors. However, it has not always been possible to directly navigate the osteotomy with real-time manipulation of available surgical tools. Registration techniques vary, although most existing systems use some form of surface matching.

Questions/purposes: We developed and evaluated a workflow model of computer-assisted bone tumor surgery and evaluated (1) the applicability of currently available software to different bones; (2) the accuracy of the navigated excision; and (3) the accuracy of a new registration technique of fluoro-CT matching.

Methods: Our workflow involved detailed preoperative planning with CT-MRI image fusion, three-dimensional mapping of the tumor, and planning of the resection plane. Using the workflow model, we reviewed 15 navigation procedures in 12 patients, including four with joint-saving resections and three with custom implant reconstructions. Intraoperatively, registration was performed with either paired points and surface matching (Group 1, n = 10) or a new technique of fluoro-CT image matching (Group 2, n = 5). All osteotomies were performed under direct computer navigation. Postoperatively, each case was evaluated for histologic margin and gross measurement of the achieved surgical margin.

Results: The margins were free from tumor in all resected specimens. In the Group 1 procedures, the correlation between preoperative planned margins and actual achieved margins was 0.631, whereas in Group 2 procedures (fluoro-CT matching), the correlation was 0.985.

Conclusions: Our findings suggest computer-assisted navigation is accurate and useful for bone tumor surgery. The new registration technique using fluoro-CT matching may allow more accurate resection of margins.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Bone Neoplasms / diagnostic imaging
  • Bone Neoplasms / mortality
  • Bone Neoplasms / secondary
  • Bone Neoplasms / surgery*
  • Child
  • China
  • Female
  • Fluoroscopy
  • Humans
  • Image Interpretation, Computer-Assisted
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Osteotomy / instrumentation
  • Osteotomy / methods*
  • Predictive Value of Tests
  • Prosthesis Implantation / instrumentation
  • Prosthesis Implantation / methods*
  • Surgery, Computer-Assisted* / instrumentation
  • Time Factors
  • Tomography, X-Ray Computed* / instrumentation
  • Treatment Outcome
  • Workflow*
  • Young Adult