Sulfonamides of 2-[(2,6-dichlorophenyl)amino]phenyl acetoxyacetic acid and their antibacterial studies

Acta Pol Pharm. 2010 Jul-Aug;67(4):351-9.

Abstract

Abstract: Reaction of 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl chloride 2 with various N'-(substituted aryl)-p-aminobenzenesulfonamide derivatives afforded title compounds. All the final compounds were characterized by the IR spectral data and elemental analysis and screened for antibacterial activity against Gram positive and Gram negativebacterial strains.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Infective Agents / chemical synthesis*
  • Anti-Infective Agents / pharmacology*
  • Bacteria / drug effects
  • Diclofenac / analogs & derivatives*
  • Diclofenac / chemical synthesis
  • Diclofenac / pharmacology
  • Dimethyl Sulfoxide
  • Indicators and Reagents
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Solvents
  • Spectrophotometry, Infrared
  • Spectroscopy, Fourier Transform Infrared
  • Structure-Activity Relationship
  • Sulfonamides / chemical synthesis*
  • Sulfonamides / pharmacology*

Substances

  • Anti-Infective Agents
  • Indicators and Reagents
  • Solvents
  • Sulfonamides
  • Diclofenac
  • aceclofenac
  • Dimethyl Sulfoxide