Task-specific ionic liquid-assisted extraction and separation of astaxanthin from shrimp waste

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Aug 15;878(24):2243-8. doi: 10.1016/j.jchromb.2010.06.034. Epub 2010 Jul 3.


Astaxanthin, as an outstanding antioxidant reagent, was successfully extracted from shrimp waste by the ionic liquids based ultrasonic-assisted extraction. Seven kinds of imidazolium ionic liquids with different cations and anions were investigated in this work and one task-specific ionic liquid in ethanol with 0.50molL(-1) was selected as the solvent. At the optimized ultrasonic extraction conditions, the extraction amount of astaxanthin increased 98% (92.7microg g(-1)) compared to the conventional method (46.7microg g(-1)). Furthermore, the extracted solution was isolated through the solid-phase extraction with a molecularly imprinted polymer sorbent. After loading the samples on molecularly imprinted polymer cartridge, the different washing and elution solvents, such as water, methanol, n-hexane, acetone and dichloromethane, were evaluated, and finally, astaxanthin was separated from the shrimp waste extract.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Calibration
  • Chemical Fractionation / methods*
  • Chromatography, High Pressure Liquid
  • Decapoda*
  • Food Industry
  • Industrial Waste
  • Ionic Liquids / chemistry
  • Meat*
  • Solvents / chemistry
  • Xanthophylls / chemistry
  • Xanthophylls / isolation & purification


  • Industrial Waste
  • Ionic Liquids
  • Solvents
  • Xanthophylls
  • astaxanthine