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Review
. 2010 Sep;12(5):440-5.
doi: 10.1007/s11886-010-0129-2.

Contrast-induced acute kidney injury: the at-risk patient and protective measures

Jeremiah R Brown  1 , Craig A Thompson
Affiliations
Review

Contrast-induced acute kidney injury: the at-risk patient and protective measures

Jeremiah R Brown et al. Curr Cardiol Rep. 2010 Sep.

Abstract

Contrast-induced acute kidney injury (CI-AKI) is a major complication following radiocontrast procedures. In this review, we characterize the recent literature on CI-AKI, risk factors, prevention, biomarkers, and new technologies. The premise of CI-AKI prophylaxis should focus on implementing mandatory standing orders before and after cardiac catheterization for hydration with normal saline or sodium bicarbonate and use of high-dose (1200-mg) N-acetylcysteine. Contrast agents may play a role in preventing CI-AKI. Implement catheter-laboratory technology and awareness to limit the amount of contrast dye used for any patient.

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