Prevalence of and risk factors for primary open-angle glaucoma in central Sri Lanka: the Kandy eye study

Ophthalmic Epidemiol. 2010 Aug;17(4):211-6. doi: 10.3109/09286586.2010.483753.


Purpose: To report the prevalence and risk factors associated with primary open-angle glaucoma (POAG) in the Kandy district of central Sri Lanka.

Methods: A cross-sectional, population-based ophthalmic survey of the inhabitants >or= 40 years of age from villages in the Kandy District, Sri Lanka was conducted. Selection was randomized using a cluster sampling process; 1721 eligible participants were identified, 1375 participated in the study and sufficient examination data to diagnose glaucoma in at least one eye was obtained in 1244 participants. A detailed ophthalmic history and examination including ocular biometry was made of each participant. Primary open-angle glaucoma was classified into three levels according to diagnostic evidence.

Results: The overall prevalence of POAG was 2.3% (95% CI 1.5-3.2). In the univariate analyses, increasing age (P = 0.001), intraocular pressure (IOP) (P < 0.001), myopia (P < 0.001) and axial length (P = 0.003) were significantly associated with POAG. In the multivariate analysis, age (P = 0.001), mean IOP (P < 0.001) and mean axial length (P = 0.008) were significant risk factors of POAG.

Conclusions: The prevalence of POAG in the population aged >or=40 years in central Sri Lanka was 2.3%. POAG in this population was independently associated with increasing age, IOP and axial length.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Cluster Analysis
  • Cross-Sectional Studies
  • Female
  • Glaucoma, Open-Angle / diagnosis
  • Glaucoma, Open-Angle / epidemiology*
  • Humans
  • Intraocular Pressure
  • Male
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Sex Distribution
  • Sri Lanka / epidemiology