The mysterious ways of the chemokine CXCL5

Immunity. 2010 Jul 23;33(1):7-9. doi: 10.1016/j.immuni.2010.07.012.


The chemokine receptor CXCR2 binds several chemokines, some of them with functions yet to be defined. In this issue of Immunity, Mei et al. (2010) generated CXCL5-deficient mice and described a prominent role of CXCL5 in the regulation of CXCR2-dependent neutrophil trafficking during pulmonary host defense.

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