[Effects of flow diverter with low porosity on cerebral aneurysms: a numerical stimulative study]

Zhonghua Yi Xue Za Zhi. 2010 Apr 20;90(15):1024-7.
[Article in Chinese]


Objective: To examine the influence of flow diverter on the alterations of cerebral intra-aneurysmal hemodynamics.

Methods: One wide-necked and one narrow-necked sidewall aneurysm in curved vessels were virtually reconstructed. Pulsatile computational fluid simulations were performed on each model for hemodynamic analysis. And the flow diverters were virtually deployed to cover the aneurysmal neck with parent vessels. The hemodynamic changes in parent vessels and aneurysms after a deployment of flow diverter devices with low porosity were studied by the Fluent software.

Results: After a deployment of flow diverter, the hemodynamics in aneurysm sac changed significantly. The peak velocity and wall stress strength in impingement zone of narrow-necked aneurysms decreased after the placement of a flow diverter. And similar change also occurred in wide-necked aneurysms, but with a less decreased span.

Conclusion: Numerical simulation confirms that a flow diverter with low porosity significantly may modify the hemodynamics in aneurysms. Which is important for prevention of bleeding or rebleeding of intracranial aneurysm.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Flow Velocity
  • Hemodynamics
  • Imaging, Three-Dimensional
  • Intracranial Aneurysm / physiopathology*
  • Intracranial Aneurysm / therapy
  • Models, Cardiovascular*
  • Numerical Analysis, Computer-Assisted*
  • Regional Blood Flow
  • Stents