MicroRNAs: genetically sensitized worms reveal new secrets

Curr Biol. 2010 Jul 27;20(14):R598-600. doi: 10.1016/j.cub.2010.05.054.

Abstract

Why do many microRNA gene mutants display no evident phenotype? Multiply mutant worms that are selectively impaired in genetic regulatory network activities have been used to uncover previously unknown functions for numerous Caenorhabditis elegans microRNAs.

Publication types

  • Comment

MeSH terms

  • Animals
  • Caenorhabditis elegans / genetics*
  • Gene Deletion
  • Gene Regulatory Networks / genetics*
  • MicroRNAs / genetics*
  • MicroRNAs / physiology*
  • Models, Genetic
  • Mutation / genetics
  • Phenotype*

Substances

  • MicroRNAs