Mitochondrial dynamics: quantifying mitochondrial fusion in vitro

BMC Biol. 2010 Jul 26;8:99. doi: 10.1186/1741-7007-8-99.

Abstract

Mitochondrial fusion is an essential process for preserving the integrity and stability of mitochondrial DNA; however, regulation of this process remains largely mysterious. In this issue of BMC Biology, Schauss and colleagues describe a simple, reliable, and robust novel assay that allows fusion of mammalian mitochondria to be quantified in vitro.

Publication types

  • Comment

MeSH terms

  • Humans
  • Membrane Fusion*
  • Mitochondria / metabolism*
  • Mitochondrial Membranes / metabolism*
  • Mitochondrial Proteins / metabolism

Substances

  • Mitochondrial Proteins