Contribution of male age to outcomes in assisted reproductive technologies

Fertil Steril. 2011 Jan;95(1):147-51. doi: 10.1016/j.fertnstert.2010.06.039. Epub 2010 Jul 21.

Abstract

Objective: To evaluate the relationship between male age and pregnancy outcome in donor oocyte assisted reproductive technology cycles.

Design: Retrospective cohort.

Setting: Private IVF center.

Patient(s): A total of 1,392 donor cycles from 1,083 female recipients and their male partners.

Intervention(s): Oocyte donor cycles.

Main outcome measure(s): Live birth.

Result(s): Increasing male age was associated with semen parameters including volume and motility; however, male age was not observed to have a statistically significant association with likelihood of live birth in donor cycles after adjustment for female recipient age.

Conclusion(s): When treatment cycle number and female recipient age were taken into account, male age had no significant association with pregnancy outcomes in assisted reproductive technology donor cycles in this study population.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Age Distribution
  • Cohort Studies
  • Female
  • Humans
  • Infertility, Female / epidemiology*
  • Infertility, Female / therapy*
  • Male
  • Middle Aged
  • Oocyte Donation / statistics & numerical data*
  • Paternal Age*
  • Pregnancy
  • Pregnancy Outcome / epidemiology*
  • Pregnancy Rate
  • Reproductive Techniques, Assisted*
  • Retrospective Studies
  • Young Adult