Obesity and age affect male fertility potential

Fertil Steril. 2010 Dec;94(7):2898-901. doi: 10.1016/j.fertnstert.2010.06.047. Epub 2010 Jul 29.

Abstract

A case-cohort study of 2,157 patients, aged 17-67 years was performed to assess the impact of body mass index and age on male fertility. Using a multiple regression analysis across the total cohort, only age correlated significantly with all spermiogram parameters and serum hormones, but in patients aged 20-30 years (n = 617) the total sperm count was significantly negatively correlated with body mass index.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aging / blood
  • Aging / physiology*
  • Body Mass Index
  • Fertility / physiology*
  • Follicle Stimulating Hormone / blood
  • Humans
  • Infertility, Male / blood
  • Infertility, Male / epidemiology
  • Infertility, Male / etiology*
  • Inhibins / blood
  • Male
  • Middle Aged
  • Obesity / blood
  • Obesity / complications*
  • Obesity / epidemiology
  • Semen Analysis
  • Young Adult

Substances

  • inhibin B
  • Inhibins
  • Follicle Stimulating Hormone