Intramuscular gold therapy is associated with long survival in patients with rheumatoid arthritis

J Rheumatol. 1991 Apr;18(4):524-9.


To investigate whether the premature death of patients with rheumatoid arthritis (RA) was associated with intramuscular (im) gold treatment or side effects due to gold, a sample of 573 adult patients with RA treated at hospital for the first time during 1961-66 was retrospectively studied for the duration and side effects of im gold treatment as well as death and causes of death. By 1989 a total of 251 patients had died. Gold treatment was not associated with premature death. On the contrary, longterm gold treatment was associated with a high survival rate. Secondary amyloidosis was diagnosed in 28 out of 63 patients, who had gold associated renal disease and who died.

MeSH terms

  • Adult
  • Arthritis, Rheumatoid / drug therapy*
  • Arthritis, Rheumatoid / mortality
  • Female
  • Follow-Up Studies
  • Gold / administration & dosage
  • Gold / therapeutic use*
  • Humans
  • Injections, Intramuscular
  • Male
  • Survival Analysis


  • Gold