This eighth and final report of the Immunization Safety Review Committee examines the hypothesis that vaccines, specifically the measles-mumps-rubella (MMR) vaccine and thimerosal-containing vaccines, are causally associated with autism. The committee reviewed the extant published and unpublished epidemiological studies regarding causality and studies of potential biologic mechanisms by which these immunizations might cause autism. The committee concludes that the body of epidemiological evidence favors rejection of a causal relationship between the MMR vaccine and autism. The committee also concludes that the body of epidemiological evidence favors rejection of a causal relationship between thimerosal-containing vaccines and autism. The committee further finds that potential biological mechanisms for vaccine-induced autism that have been generated to date are theoretical only. The committee does not recommend a policy review of the current schedule and recommendations for the administration of either the MMR vaccine or thimerosal-containing vaccines. The committee recommends a public health response that fully supports an array of vaccine safety activities. In addition, the committee recommends that available funding for autism research be channeled to the most promising areas. The committee makes additional recommendations regarding surveillance and epidemiological research, clinical studies, and communication related to these vaccine safety concerns. Please see Box ES-1 for a summary of all conclusions and recommendations.
Copyright © 2004, National Academy of Sciences.
Use of Combination Measles, Mumps, Rubella, and Varicella Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP)M Marin et al. MMWR Recomm Rep 59 (RR-3), 1-12. PMID 20448530.This report presents new recommendations adopted in June 2009 by CDC's Advisory Committee on Immunization Practices (ACIP) regarding use of the combination measles, mumps …
A Comparative Evaluation of the Effects of MMR Immunization and Mercury Doses From Thimerosal-Containing Childhood Vaccines on the Population Prevalence of AutismDA Geier et al. Med Sci Monit 10 (3), PI33-9. PMID 14976450.The results of this study agree with a number of previously published studies. These studies have shown that there is biological plausibility and epidemiological evidence …
Closer Look at Autism and the Measles-Mumps-Rubella VaccineE Hensley et al. J Am Pharm Assoc (2003) 50 (6), 736-41. PMID 21071320. - ReviewThe evidence presented does not show a causal relationship between the MMR vaccine and autism. Myths presented to potentially support any relationship between the MMR vac …
Prevention of Measles, Rubella, Congenital Rubella Syndrome, and Mumps, 2013: Summary Recommendations of the Advisory Committee on Immunization Practices (ACIP)HQ McLean et al. MMWR Recomm Rep 62 (RR-04), 1-34. PMID 23760231.This report is a compendium of all current recommendations for the prevention of measles, rubella, congenital rubella syndrome (CRS), and mumps. The report presents the r …
Immunization Safety Review: Measles-Mumps-Rubella Vaccine and AutismInstitute of Medicine (US) Immunization Safety Review Committee. PMID 25057557. - ReviewImmunization is widely regarded as one of the most effective and beneficial tools for protecting the public's health. In the United States, immunization programs have res …