In performance of hemosorption in 108 patients with acute intoxications, 210 manipulations of Seldinger's central venous puncture and catheterization, Skribner's arteriovenous shunting, section of the basal brachial vein were accomplished. In 23 (10.1%) patients, the complications developed: hematoma at the site of puncture--in 10, puncture of the subclavian artery--in 3, puncture of the femoral artery--in 6, shunt thrombosis--in 2, catheter thrombosis--in 2. In patients with acute intoxications, the use of veno-venous method of hemosorption with Seldinger's catheterization of the subclavian and femoral veins is preferrable.