Surgical management of primary central nervous system germ cell tumors: proceedings from the Second International Symposium on Central Nervous System Germ Cell Tumors

J Neurosurg Pediatr. 2010 Aug;6(2):125-30. doi: 10.3171/2010.5.PEDS09112.

Abstract

The successful treatment of children with a primary CNS germ cell tumor can be greatly influenced by the neurosurgeon involved in the diagnostic and therapeutic care of these children. Variability in surgical philosophies no doubt exists due to the relatively infrequent incidence of these tumors, a lack of consensus regarding diagnostic and therapeutic approaches, and the advent of recent surgical innovations. Many of these issues were discussed at the Second International Symposium on Central Nervous System Germ Cell Tumors through presented abstracts and invited presentations. The neurosurgical aspects of these proceedings are summarized here in an effort to present the agreed-upon and debated issues that may confront the pediatric neurosurgeon.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / cerebrospinal fluid
  • Biopsy
  • Brain / pathology
  • Brain / surgery
  • Brain Neoplasms / drug therapy
  • Brain Neoplasms / pathology
  • Brain Neoplasms / radiotherapy
  • Brain Neoplasms / surgery*
  • Child
  • Combined Modality Therapy
  • Diagnostic Imaging
  • Endoscopy / methods
  • Female
  • Germinoma / drug therapy
  • Germinoma / pathology
  • Germinoma / radiotherapy
  • Germinoma / surgery
  • Humans
  • Male
  • Microsurgery
  • Neoadjuvant Therapy
  • Neoplasm Recurrence, Local / drug therapy
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / radiotherapy
  • Neoplasm Recurrence, Local / surgery
  • Neoplasms, Germ Cell and Embryonal / drug therapy
  • Neoplasms, Germ Cell and Embryonal / pathology
  • Neoplasms, Germ Cell and Embryonal / radiotherapy
  • Neoplasms, Germ Cell and Embryonal / surgery*
  • Neuronavigation
  • Reoperation

Substances

  • Biomarkers, Tumor