Keloids: pathogenesis, clinical features, and management

Semin Plast Surg. 2009 Aug;23(3):178-84. doi: 10.1055/s-0029-1224797.


Cutaneous wound healing is a complex response to skin injury. Deregulation of this process can lead to excessive scar formation, as seen in keloids. Keloids are common skin lesions that are difficult to treat and are associated with high recurrence rates despite the large number of available treatment options. With increased knowledge of the disease process and further scientific advancements, future approaches will hopefully improve keloid treatment. In this article, we review the epidemiology, genetic basis, etiology, clinical features, pathogenesis, and management of keloids.

Keywords: Keloid; hypertrophic scar; treatment.