Comment on 'Estimating average annual per cent change in trend analysis' by Clegg LX, Hankey BF, Tiwari R, Feuer EJ, Edwards BK, Statistics in Medicine 2009; 28:3670-3682

Stat Med. 2010 Aug 15;29(18):1958-60; author reply 1961. doi: 10.1002/sim.3850.


We discuss some issues relevant to paper of Clegg and co-authors published in Statistics in Medicine; 28, 3670-3682. Emphasis is on computation of the variance of the sum of products of two estimates, slopes and breakpoints.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Algorithms
  • Data Interpretation, Statistical*
  • Female
  • Humans
  • Male
  • Nonlinear Dynamics*
  • Racial Groups
  • Time Factors