Application of a cardiovascular disease risk prediction model among commercial pilots

Aviat Space Environ Med. 2010 Aug;81(8):768-73. doi: 10.3357/asem.2748.2010.

Abstract

Introduction: It has been suggested that integrated cardiovascular risk management guidelines and absolute cardiovascular risk prediction scores should be used routinely in aeromedical risk assessment. In this study a cardiovascular disease (CVD) risk prediction model has been applied to UK commercial pilots as an occupational group.

Method: This retrospective cross-sectional study measured the variables age, sex, body mass index (BMI), blood pressure, use of antihypertensive medication, current smoking, and diabetes status of commercial pilots. Individual 10-yr absolute CVD risk scores (also referred to as 10-yr global CVD risk) were calculated using a non-laboratory based Framingham Heart Study developed model.

Results: Of the 14,379 subjects eligible for the study, none had missing values for risk factors. None of the female pilots and 9.7% of all male pilots were found to be high risk. The mean 10-yr absolute CVD risk for the entire pilot population was 8.41% (median 5.6). High-risk pilots are concentrated around 60 yr of age, (mean 59, median 60 yr) with an age range of 40-81 yr. A sub-analysis of high-risk pilots younger than 65 revealed 1137 pilots in this group.

Conclusion: The application of a 10-yr absolute CVD risk prediction model identified a group of pilots, previously unidentified, who may require a more comprehensive risk assessment. Pilots are continuing to fly commercially beyond the age of 60, which results in substantial increase in the CVD risk burden of the pilot population as a whole.

MeSH terms

  • Adult
  • Aerospace Medicine*
  • Age Factors
  • Aged
  • Antihypertensive Agents / therapeutic use
  • Cardiovascular Diseases / diagnosis*
  • Commerce
  • Cross-Sectional Studies
  • Diabetes Mellitus / epidemiology
  • Female
  • Humans
  • Hypertension / diagnosis*
  • Hypertension / drug therapy
  • Hypertension / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • Risk Assessment
  • Risk Factors
  • Sex Distribution
  • United Kingdom / epidemiology

Substances

  • Antihypertensive Agents