Toxicity of 3-methyleneoxindole, a proposed reactive intermediate in the metabolism of 3-methylindole

Adv Exp Med Biol. 1991:283:245-8. doi: 10.1007/978-1-4684-5877-0_24.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Biotransformation
  • Cell Survival / drug effects
  • Cytochrome P-450 Enzyme System / metabolism
  • Indoles / metabolism
  • Indoles / toxicity*
  • Lethal Dose 50
  • Lung / cytology
  • Lung / drug effects
  • Male
  • Mice
  • Oxindoles
  • Skatole / metabolism
  • Skatole / toxicity

Substances

  • Indoles
  • Oxindoles
  • 3-methyleneoxindole
  • Cytochrome P-450 Enzyme System
  • Skatole