A long affair with renal tubules

Annu Rev Physiol. 2011;73:1-28. doi: 10.1146/annurev-physiol-012110-142241.


This essay provides a summary of my professional activities. My interest in renal physiology started as a medical student in Vienna, when I became acquainted with Homer Smith's essays on kidney function. After moving to the United States in 1951, I was fortunate to be mentored by Robert Pitts, in whose Department of Physiology at Cornell Medical College in New York I was given early independence, intellectual stimulation, and the opportunity to pursue experiments on single renal tubules. The problem of how the nephron manages its myriad of transport functions has never lost its fascination for me, and I am profoundly grateful to the many colleagues at Cornell Medical College and at Yale University School of Medicine who shared my passion for the kidney.

Publication types

  • Biography
  • Historical Article
  • Portrait

MeSH terms

  • Acid-Base Equilibrium / physiology
  • Animals
  • Female
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Kidney Tubules / physiology*
  • Male
  • Mice
  • Potassium Channels / physiology
  • Rats
  • Sodium Channels / physiology
  • Water / physiology


  • Potassium Channels
  • Sodium Channels
  • Water

Personal name as subject

  • Gerhard H Giebisch