Pulmonary manifestations of the antiphospholipid antibody syndrome

Clin Chest Med. 2010 Sep;31(3):537-45. doi: 10.1016/j.ccm.2010.05.005.


A broad spectrum of pulmonary disease may occur in antiphospholipid antibody syndrome. The most common pulmonary manifestations are pulmonary thromboembolism and pulmonary hypertension. In this article the authors review these manifestations, as well as less common findings including acute respiratory distress syndrome, alveolar hemorrhage, and pulmonary capillaritis.

Publication types

  • Review

MeSH terms

  • Antiphospholipid Syndrome / complications*
  • Hemorrhage / etiology
  • Humans
  • Hypertension, Pulmonary / etiology
  • Lung Diseases / drug therapy
  • Lung Diseases / etiology*
  • Lung Diseases / pathology
  • Pulmonary Embolism / etiology
  • Respiratory Distress Syndrome / etiology