The D2194G mutation is responsible for increased levels of FV1 in carriers of the factor V R2 haplotype

Thromb Haemost. 2010 Oct;104(4):860-1. doi: 10.1160/TH10-03-0180. Epub 2010 Aug 5.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Brefeldin A / pharmacology
  • COS Cells
  • Chlorocebus aethiops
  • Endoplasmic Reticulum / drug effects
  • Factor V / genetics
  • Factor V / metabolism*
  • Glycosylation / drug effects
  • Haplotypes
  • Heterozygote
  • Humans
  • Mutation / genetics*
  • Protein Folding
  • Protein Isoforms / genetics
  • Protein Isoforms / metabolism*
  • Protein Transport / drug effects
  • Protein Transport / genetics
  • Transgenes / genetics

Substances

  • Protein Isoforms
  • Brefeldin A
  • Factor V