Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010;54(5):477-81.
doi: 10.1590/s0004-27302010000500008.

Normal Values of Serum IGF-1 in Adults: Results From a Brazilian Population


Normal Values of Serum IGF-1 in Adults: Results From a Brazilian Population

Pedro Weslley Rosario. Arq Bras Endocrinol Metabol. .


Objective: To determine the normal values of serum IGF-1 (Immulite 2000) in a Brazilian adult (21-70 years) population.

Subjects and methods: Healthy volunteers were divided into 10 groups according to age (5-year intervals), with 100 subjects (50 men and 50 women) per group. One-hundred participants were selected for repetition of the test after 12 weeks.

Results: No difference in IGF-1 values was observed between men and women, but a progressive reduction of serum IGF-1 with age was seen. The reference values provided by the manufacturer of the assay, although discretely higher, were very close to the values found in this study. A second measurement of IGF-1 after 12 weeks revealed a variation < 20% in 99% of subjects.

Conclusions: This study established the reference range for IGF-1 determined with the Immulite 2000 assay for a large number of healthy Brazilian adults stratified according to age, and suggests that variations > 20% in IGF-1 levels within an interval of 12 weeks cannot be attributed to interassay variability.

Similar articles

See all similar articles

Cited by 14 articles

See all "Cited by" articles

Publication types


LinkOut - more resources