MASiVE: Mapping and Analysis of Sirevirus Elements in plant genome sequences

Bioinformatics. 2010 Oct 1;26(19):2452-4. doi: 10.1093/bioinformatics/btq454. Epub 2010 Aug 9.


We present MASiVE, an expertly built tool for the large-scale, yet sensitive and highly accurate, discovery, preliminary analysis and insertion age estimation of intact Sirevirus LTR-retrotransposons in plant genomic sequences. Validation was based on the recently available and annotated large maize chromosome one. Results show a considerable improvement in the annotation of Sireviruses, and support our approach as an important addition to the bioinformatics toolbox of plant biologists.

Availability: PERL source code and essential files are available online at The freely available Vmatch, LTRharvest, Wise2, and MAFFT algorithms are required.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Computational Biology / methods*
  • Databases, Genetic
  • Genome, Plant*
  • Genome, Viral
  • Retroelements / genetics*
  • Sequence Analysis, DNA / methods
  • Software*
  • Zea mays / genetics


  • Retroelements