Malignant melanoma metastatic to the larynx: treatment and functional outcome

Curr Oncol. 2010 Aug;17(4):127-32. doi: 10.3747/co.v17i4.515.


The review considers management strategies for malignant melanoma metastatic to the larynx. This rare clinical entity lacks clear treatment recommendations because extirpative surgery can often result in severe functional debilitation in patients with limited life expectancy. Here, we report a case of melanoma metastatic to the larynx in a patient with a prior history of Hodgkin lymphoma. The patient was treated with partial laryngectomy and local radiation therapy. The rationale for treatment decisions and for surgical and radiotherapeutic techniques and the associated literature are discussed.

Keywords: Laryngeal melanoma; mucosal melanoma.