The effect of epidermal growth factor on corneal wound healing: practical considerations for therapeutic use

Refract Corneal Surg. May-Jun 1991;7(3):232-9.


Modulation of wound healing is particularly important for the corneal and refractive surgeon. At least some of the unpredictability in effect observed following radial keratotomy, penetrating keratoplasty, and photorefractive keratectomy, as well as the failure of epikeratoplasty may be explained by the variations in wound healing.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Cornea / metabolism
  • Cornea / surgery*
  • Epidermal Growth Factor / metabolism
  • Epidermal Growth Factor / pharmacology*
  • ErbB Receptors / metabolism
  • Molecular Sequence Data
  • Transforming Growth Factor alpha / metabolism
  • Wound Healing / drug effects*


  • Transforming Growth Factor alpha
  • Epidermal Growth Factor
  • ErbB Receptors