Graves' thyrotoxicosis and Moyamoya disease

Can J Neurol Sci. 1991 May;18(2):140-2. doi: 10.1017/s0317167100031607.


Cerebrovascular accidents due to Moyamoya disease, a disorder characterized by arterial stenosis at the base of the brain accompanied by typical net-like collateral vessels, occurred in two young Japanese women with Graves' disease when they were in thyrotoxicosis. In one patient, a second attack of cerebral infarction occurred with the recurrence of thyrotoxicosis. Association of Moyamoya disease and Graves' thyrotoxicosis is rare and the pathegenetic relationship is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cerebral Angiography
  • Female
  • Graves Disease / blood
  • Graves Disease / complications*
  • Humans
  • Moyamoya Disease / complications*
  • Moyamoya Disease / diagnostic imaging
  • Thyroid Hormones / blood
  • Thyrotoxicosis / blood
  • Thyrotoxicosis / etiology*
  • Tomography, X-Ray Computed


  • Thyroid Hormones