Newborn screening healthcare information system based on service-oriented architecture

J Med Syst. 2010 Aug;34(4):519-30. doi: 10.1007/s10916-009-9265-x. Epub 2009 Mar 24.


In this paper, we established a newborn screening system under the HL7/Web Services frameworks. We rebuilt the NTUH Newborn Screening Laboratory's original standalone architecture, having various heterogeneous systems operating individually, and restructured it into a Service-Oriented Architecture (SOA), distributed platform for further integrity and enhancements of sample collections, testing, diagnoses, evaluations, treatments or follow-up services, screening database management, as well as collaboration, communication among hospitals; decision supports and improving screening accuracy over the Taiwan neonatal systems are also addressed. In addition, the new system not only integrates the newborn screening procedures among phlebotomy clinics, referral hospitals, as well as the newborn screening center in Taiwan, but also introduces new models of screening procedures for the associated, medical practitioners. Furthermore, it reduces the burden of manual operations, especially the reporting services, those were heavily dependent upon previously. The new system can accelerate the whole procedures effectively and efficiently. It improves the accuracy and the reliability of the screening by ensuring the quality control during the processing as well.

MeSH terms

  • Hospital Information Systems*
  • Humans
  • Infant, Newborn
  • Information Storage and Retrieval / methods*
  • Internet
  • Local Area Networks*
  • Neonatal Screening*