New onset type 1 diabetes presenting as ketoacidosis simultaneously presenting with autoimmune hyperthyroidism--a case report

J Diabetes Complications. May-Jun 2011;25(3):208-10. doi: 10.1016/j.jdiacomp.2010.06.002. Epub 2010 Aug 12.


Autoimmune conditions are common with an estimated prevalence in the UK of 2.5%. The presence of one condition should always prompt the clinician to look for others if new symptoms arise. Autoimmune polyglandular syndromes are well described. However, it is unusual for two or more autoimmune conditions to present simultaneously. We describe a case of two autoimmune conditions--type 1 diabetes and Graves' disease--being diagnosed for the first time in the same individual at the same visit to the emergency department. We suggest that thyrotoxicosis be added to the list of potential precipitants for diabetic ketoacidosis.

Publication types

  • Case Reports

MeSH terms

  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 1 / diagnosis
  • Diabetic Ketoacidosis / diagnosis
  • Diabetic Ketoacidosis / etiology*
  • Humans
  • Hyperthyroidism / complications*
  • Hyperthyroidism / diagnosis
  • Male
  • Thyroiditis, Autoimmune / complications*
  • Thyroiditis, Autoimmune / diagnosis
  • Thyrotoxicosis / complications*
  • Thyrotoxicosis / diagnosis
  • Young Adult