The uncommon causes of status epilepticus: a systematic review

Epilepsy Res. 2010 Oct;91(2-3):111-22. doi: 10.1016/j.eplepsyres.2010.07.015. Epub 2010 Aug 14.


This paper reports the first systematic review of uncommon causes of status epilepticus reported in the literature between 1990 and 2008. Uncommon causes are defined as those not listed in the main epidemiological studies of status epilepticus. 181 causes were identified. These were easily categorised into 5 specific aetiological categories: immunological disorders, mitochondrial disorders, infectious diseases, genetic disorders and drugs/toxins. A sixth category of 'other causes' has also been included. Knowledge of these causes is important for clinical management and treatment, and also for a better understanding of the pathophysiology of status epilepticus.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Animals
  • Communicable Diseases / complications*
  • Drug-Related Side Effects and Adverse Reactions
  • Humans
  • Immune System Diseases / complications*
  • Status Epilepticus / chemically induced
  • Status Epilepticus / etiology*
  • Status Epilepticus / genetics
  • Status Epilepticus / physiopathology