The application of minerals in managing alcohol hangover: a preliminary review

Curr Drug Abuse Rev. 2010 Jun;3(2):110-5. doi: 10.2174/1874473711003020110.


Despite the high prevalence and economic burden, biological mechanisms and effective treatments of alcohol hangover are not well understood. We have focused on oxidative stress and inflammatory responses which would substantially contribute to hangover physiology and symptoms based on preexisting research data. And, it is considered that minerals are one of the important components and influencing factors in antioxidant and anti-inflammatory system. Moreover, mineral deficient conditions show similar symptoms that occur in alcohol hangover. Herein we review some possible implications of various minerals, such as selenium, zinc, copper, vanadium, iron, and magnesium, according to suggested mechanisms and symptoms of alcohol hangover. Although, noticeable considerations and controlled trials will be required for general recommendations, we hope that our preliminary speculation would pave the way for further understanding and managing alcohol hangover.

Publication types

  • Review

MeSH terms

  • Acetaldehyde / metabolism
  • Alcohol Drinking / immunology
  • Alcohol Drinking / metabolism
  • Alcoholic Intoxication / metabolism
  • Alcoholic Intoxication / psychology
  • Alcoholic Intoxication / therapy*
  • Cytokines / metabolism
  • Ethanol / metabolism
  • Humans
  • Inflammation / metabolism
  • Minerals / therapeutic use*
  • Oxidative Stress


  • Cytokines
  • Minerals
  • Ethanol
  • Acetaldehyde