How best to manage dysfunctional uterine bleeding

J Fam Pract. 2010 Aug;59(8):449-58.

Abstract

Irregular or unusually heavy periods are a common complaint. Most often, the condition is benign and can by managed conservatively. Assess postmenopausal women for cancer by endometrial biopsy, transvaginal ultrasound, or saline infusion sonohysterogram. Treat mild dysfunctional uterine bleeding (DUB) with nonsteroidal anti-inflammatory drugs, levonorgestrel intrauterine device (IUD), or danazol. Treat moderate DUB with oral contraceptive pills, levonorgestrel IUD, danazol, or tranexamic acid.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Biopsy
  • Contraceptive Agents, Female / therapeutic use
  • Danazol / therapeutic use
  • Diagnosis, Differential
  • Endometrium / surgery
  • Estrogen Antagonists / therapeutic use
  • Female
  • Humans
  • Intrauterine Devices
  • Levonorgestrel / therapeutic use
  • Medical History Taking
  • Metrorrhagia / diagnosis*
  • Metrorrhagia / etiology
  • Metrorrhagia / therapy*
  • Risk Factors
  • Ultrasonography

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Contraceptive Agents, Female
  • Estrogen Antagonists
  • Levonorgestrel
  • Danazol