Crustacean neuropeptides

Cell Mol Life Sci. 2010 Dec;67(24):4135-69. doi: 10.1007/s00018-010-0482-8. Epub 2010 Aug 21.


Crustaceans have long been used for peptide research. For example, the process of neurosecretion was first formally demonstrated in the crustacean X-organ-sinus gland system, and the first fully characterized invertebrate neuropeptide was from a shrimp. Moreover, the crustacean stomatogastric and cardiac nervous systems have long served as models for understanding the general principles governing neural circuit functioning, including modulation by peptides. Here, we review the basic biology of crustacean neuropeptides, discuss methodologies currently driving their discovery, provide an overview of the known families, and summarize recent data on their control of physiology and behavior.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Crustacea / anatomy & histology
  • Crustacea / chemistry*
  • Crustacea / physiology
  • Mass Spectrometry / methods
  • Molecular Sequence Data
  • Neuropeptides / analysis*
  • Neuropeptides / genetics


  • Neuropeptides