Orange juice improved lipid profile and blood lactate of overweight middle-aged women subjected to aerobic training

Maturitas. 2010 Dec;67(4):343-7. doi: 10.1016/j.maturitas.2010.07.009. Epub 2010 Aug 21.


Objective: This study investigated how consumption of orange juice associated with aerobic training affected serum lipids and physical characteristics of overweight, middle-aged women.

Methods: The experimental group consisted of 13 women who consumed 500 mL/d of orange juice and did 1h aerobic training 3 times a week for 3 months. The control group consisted of another 13 women who did the same aerobic training program but did not consume orange juice.

Results: At the end of the experiment, the control group lost an average of 15% of fat mass (P<0.05) and 2.5% of weight (P<0.05), whereas the experimental group lost 11% of fat mass and 1.2% of weight (P<0.05). Consumption of orange juice by the experimental group was associated with increased dietary intake of vitamin C and folate by 126% and 61% respectively. Serum LDL-C decreased 15% (P<0.05) and HDL-C increased 18% (P<0.05) in the experimental group, but no significant change was observed in the control group. Both groups improved the anaerobic threshold by 20% (P<0.05), but blood lactate concentration decreased 27% in the experimental group compared to the 17% control group, suggesting that experimental group has less muscle fatigue and better response to training.

Conclusions: The consumption of 500 mL/d of orange juice associated with aerobic training in overweight women decreased cardiovascular disease risk by reducing LDL-C levels and increasing HDL-C levels. This association also decreased blood lactate concentration and increased anaerobic threshold, showing some improvement in the physical performance.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / drug effects*
  • Adult
  • Anaerobic Threshold / drug effects
  • Ascorbic Acid / administration & dosage
  • Body Weight / drug effects*
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Citrus sinensis*
  • Exercise / physiology*
  • Female
  • Folic Acid / administration & dosage
  • Fruit
  • Humans
  • Lactic Acid / blood*
  • Lipids / blood*
  • Middle Aged
  • Muscle Fatigue / drug effects
  • Overweight / blood
  • Overweight / drug therapy*
  • Overweight / physiopathology
  • Phytotherapy
  • Plant Preparations / pharmacology
  • Plant Preparations / therapeutic use


  • Cholesterol, HDL
  • Cholesterol, LDL
  • Lipids
  • Plant Preparations
  • Lactic Acid
  • Folic Acid
  • Ascorbic Acid