[Fe(F(20)TPP)Cl] catalyzed intramolecular C-N bond formation for alkaloid synthesis using aryl azides as nitrogen source

Yungen Liu; Jinhu Wei; Chi-Ming Che

doi:10.1039/c0cc01825b

[Fe(F(20)TPP)Cl] catalyzed intramolecular C-N bond formation for alkaloid synthesis using aryl azides as nitrogen source

Chem Commun (Camb). 2010 Oct 7;46(37):6926-8. doi: 10.1039/c0cc01825b. Epub 2010 Aug 23.

Authors

Yungen Liu¹, Jinhu Wei, Chi-Ming Che

Affiliation

¹ Department of Chemistry and Open Laboratory of Chemical Biology of the Institute of Molecular Technology for Drug Discovery and Synthesis, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

PMID: 20730175
DOI: 10.1039/c0cc01825b

Abstract

The syntheses of alkaloids including indoles, indolines, tetrahydroquinolines, dihydroquinazolinones and quinazolinones have been accomplished in moderate to excellent yields via [Fe(F(20)TPP)Cl] catalyzed intramolecular C-N bond formation using aryl azides as nitrogen source.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkaloids / chemical synthesis*
Alkaloids / chemistry
Azides / chemistry*
Catalysis
Cyclization
Iron Compounds / chemistry*
Molecular Structure
Stereoisomerism

Substances

Alkaloids
Azides
Iron Compounds