doi: 10.1016/j.bmcl.2010.07.126.
Epub 2010 Aug 3.
Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2'-deoxyuridines
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- PMID: 20732810
- DOI: 10.1016/j.bmcl.2010.07.126
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Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2'-deoxyuridines
Bioorg Med Chem Lett.
.
Abstract
We have focused on the C5-modification of 2'-deoxyuridine with substituted heterocycles for bioactivity, such as antiviral or anticancer activity. Herein, we report a novel class of nucleoside analogues with perfluoroalkyltriazole moiety as an anticancer drug candidate.
Copyright © 2010 Elsevier Ltd. All rights reserved.
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