Biliary epithelial metastasis of squamous carcinoma of the anus

Ir J Med Sci. 2010 Dec;179(4):605-6. doi: 10.1007/s11845-010-0556-5. Epub 2010 Aug 24.


Introduction: The liver and biliary tree are common sites of initial metastasis for many primary tumors. However, we recently encountered a patient who presented with biliary-tree tumor encasement as a first metastasis from squamous carcinoma of the anus.

Methods: To our knowledge, this has not been previously described in the literature.

Conclusions: As obstructive jaundice is a relatively common presenting sign in the emergency room and in general surgical clinics, we thus recommend early consideration of metastatic disease as a differential diagnosis in patients post-chemoradiotherapy for anal carcinoma who present with obstructive jaundice.

Publication types

  • Case Reports

MeSH terms

  • Anus Neoplasms / pathology*
  • Anus Neoplasms / surgery
  • Bile Ducts / pathology
  • Biliary Tract Neoplasms / secondary*
  • Biliary Tract Neoplasms / surgery
  • Carcinoma, Squamous Cell / secondary*
  • Carcinoma, Squamous Cell / surgery
  • Common Bile Duct Neoplasms
  • Dilatation, Pathologic
  • Epithelium / pathology
  • Female
  • Humans
  • Jaundice, Obstructive / etiology
  • Jejunostomy
  • Middle Aged
  • Pancreatic Ducts / pathology