TFInfer: a tool for probabilistic inference of transcription factor activities

Bioinformatics. 2010 Oct 15;26(20):2635-6. doi: 10.1093/bioinformatics/btq469. Epub 2010 Aug 24.


Summary: TFInfer is a novel open access, standalone tool for genome-wide inference of transcription factor activities from gene expression data. Based on an earlier MATLAB version, the software has now been extended in a number of ways. It has been significantly optimised in terms of performance, and it was given novel functionality, by allowing the user to model both time series and data from multiple independent conditions. With a full documentation and intuitive graphical user interface, together with an in-built data base of yeast and Escherichia coli transcription factors, the software does not require any mathematical or computational expertise to be used effectively.



Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computational Biology
  • Databases, Factual
  • Escherichia coli / metabolism
  • Gene Expression
  • Models, Statistical*
  • Software*
  • Transcription Factors / chemistry*
  • Transcription Factors / metabolism
  • Yeasts / metabolism


  • Transcription Factors