The pharmacokinetics of cefodizime following intravenous and intramuscular administration of a single dose of 1.0 g

A Bryskier; T Procyk; D Tremblay; B Lenfant; J B Fourtillan

doi:10.1093/jac/26.suppl_c.59

The pharmacokinetics of cefodizime following intravenous and intramuscular administration of a single dose of 1.0 g

J Antimicrob Chemother. 1990 Nov:26 Suppl C:59-63. doi: 10.1093/jac/26.suppl_c.59.

Authors

A Bryskier¹, T Procyk, D Tremblay, B Lenfant, J B Fourtillan

Affiliation

¹ Institut Roussel-Uclaf, Romainville, France.

PMID: 2074252
DOI: 10.1093/jac/26.suppl_c.59

Abstract

The pharmacokinetics and absolute bioavailability of cefodizime were determined after iv and im administration of a single 1.0 g dose in eight healthy volunteers. The absolute bioavailability of cefodizime after im injection of 1.0 g was 88% and 91% when determined by two different formulae.

Publication types

Comparative Study

MeSH terms

Adult
Biological Availability
Cefotaxime / administration & dosage
Cefotaxime / analogs & derivatives*
Cefotaxime / pharmacokinetics
Chromatography, High Pressure Liquid
Half-Life
Humans
Injections, Intramuscular
Injections, Intravenous
Male

Substances

Cefotaxime
cefodizime