Development of pentamidine analogues as new agents for the treatment of Pneumocystis carinii pneumonia

Ann N Y Acad Sci. 1990;616:421-41. doi: 10.1111/j.1749-6632.1990.tb17862.x.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • DNA, Fungal / metabolism
  • Disease Models, Animal
  • Dose-Response Relationship, Drug
  • Drug Design
  • Giardia / drug effects
  • In Vitro Techniques
  • Leishmania mexicana / drug effects
  • Male
  • Pentamidine / administration & dosage
  • Pentamidine / pharmacokinetics
  • Pentamidine / pharmacology*
  • Plasmodium falciparum / drug effects
  • Pneumocystis / drug effects*
  • Pneumocystis / genetics
  • Pneumonia, Pneumocystis / drug therapy*
  • Rats
  • Rats, Inbred Strains
  • Structure-Activity Relationship

Substances

  • DNA, Fungal
  • Pentamidine