Abstract
Congenital nemaline myopathy (CNM) is generally classified as a non-progressive or slowly progressive neuromuscular disease. We describe a boy with CNM and an isolated partial growth hormone (GH) deficiency. From the onset of GH therapy his respiratory capacity deteriorated rapidly. The possible association between this deterioration and GH therapy is discussed.
MeSH terms
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Adolescent
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Growth Hormone / adverse effects*
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Growth Hormone / pharmacology
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Humans
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Hypoventilation / chemically induced*
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Hypoventilation / etiology
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Male
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Muscles / drug effects
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Neuromuscular Diseases / complications
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Neuromuscular Diseases / congenital*
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Respiratory Insufficiency / chemically induced
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Respiratory Insufficiency / etiology
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Scoliosis / complications